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E-Newsletter • April 2024 |
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Editor's E-Note
Ultrasound is a highly useful diagnostic modality, but it is slowly moving into the treatment realm, as well. Already used clinically for essential tremor, focused ultrasound is being investigated for additional uses. In this month’s newsletter, we’re highlighting research that aims to use ultrasound to treat chronic pain and depression.
Does your facility perform focused ultrasound? Please let us know on X, formerly known as Twitter, and/or Facebook.
Enjoy the newsletter.
— Dave Yeager, editor |
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Treating Chronic Pain With Ultrasound
Those struggling with chronic pain or depression often report feeling “hopeless” or “despairing” when multiple therapies and interventions have not provided relief. Such people, however, described their experience in more hopeful terms after participating in a recent study of a new biomedical technology developed at the University of Utah.
“This is the first time in three years I’ve felt like myself. It feels like my brain has been woken up,” one patient said. Others said, “That trauma is no longer with me. It is finally gone,” and “I was walking around the grocery store and just felt so clear. I was wondering, is this what normal people feel like?”
The device at the center of these human clinical trials, called Diadem, promises to change how certain neurological disorders are treated. Resembling a pair of oversized headphones, it stimulates regions of the deep brain underlying chronic pain and depression—with the power and precision of focused ultrasound. Diadem’s creators are now seeking volunteers to participate in its final phase of clinical trials needed to obtain regulatory approval and provide these treatments at a large scale.
“We’ve been blown away by the positive results so far,” says the paper’s lead author, Tom Riis, a postdoctoral researcher in the department of biomedical engineering. “After just a single 40-minute stimulation session, patients are showing immediate, clinically substantial improvements in symptoms.”
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Molecular Subtypes May Hold Key to Better Kidney Cancer Treatment
Yale Cancer Center researchers published a study in Cancer Cell in which they differentiated molecular subgroups of renal cell carcinoma tumors to better learn how to treat them.
Noninvasive CT Imaging Could Improve Follow-Up Imaging
A study published in Radiology: Cardiothoracic Imaging revealed that noninvasive CT imaging could better help identify patients in need of follow-up imaging for artery blockages.
Targeting Brain Tumor Proteins Shows Promise for Reducing Tumor Size
Early trials reveal that targeting two “brain-associated proteins” could prove to be a promising treatment to reduce tumor size and growth, according to findings published in a study from Nature Medicine. |
“Our research suggests that special brain scan markers could one day help doctors customize treatment plans for brain cancer patients, potentially making treatments more effective. However, we're still early in our journey, needing more studies to truly understand how to use these markers effectively and ensure they work for everyone.”
— Thomas Booth, a reader in neuroimaging in the School of Biomedical Engineering and Imaging Sciences at King’s College London, and coauthor of a review investigating MRI’s usefulness in identifying biomarkers in brain cancer |
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