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Although mammography is still the gold standard for breast cancer screening, research continues to illuminate the value of digital breast tomosynthesis. In this month’s newsletter, we’re highlighting a recent study that found a reduction in interval cancers among women who received DBT compared with women who received mammography. While more research needs to be done, the future of DBT as a screening tool seems highly promising.
Let us know your thoughts about DBT vs mammography on Twitter and/or Facebook.
Enjoy the newsletter.
— Dave Yeager, editor |
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DBT Reduces Rate of Interval Cancers
Screening with digital breast tomosynthesis (DBT) reduces the rate of interval breast cancers compared with screening with digital mammography, according to a study published in Radiology. The study adds to a growing body of evidence supporting DBT as a breast cancer screening tool with important advantages over mammography. DBT works by capturing a series of X-ray images of the breast from different angles. Previous research has shown that it has a higher sensitivity for breast cancer detection than digital mammography.
The impact of these additional DBT-detected cancers is not fully understood. While they may constitute a screening benefit, they could also contribute to overdiagnosis, a term for the diagnosis of early-stage, slow-growing cancers that would not have caused harm to the patient in their lifetime. The rate of interval cancers—cancers that arise between routine screenings—offers one way to better elucidate screening benefits. They are considered more aggressive than cancers detected during a screening exam.
“Interval cancers have, in general, a more aggressive biological profile than screen-detected cancers,” says study lead author Kristin Johnson, MD, a radiology resident at Skåne University Hospital in Malmö and a PhD student at Lund University in Sweden. “This means that the prognosis is less favorable for interval cancers compared to screen-detected cancers.”
Interval cancer detection rate reporting is required in many screening programs as an indicator of effectiveness. A reduction in the interval cancer rate when using DBT may be attributed to improved detection of rapidly growing cancers with poorer prognosis, possibly contributing to lower breast cancer mortality.
Full story » |
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Worst-Case Scenario
When planning ahead for triage and other emergency circumstances, radiologists need to anticipate a host of variables associated with staffing, venues, and equipment. Read more »
Change in Programming
The industry is applauding several newly expanded lung cancer screening protocols and forecasting that increased eligibility will translate into thousands of lives saved. Read more »
Doppler Shift
A long-undervalued tool for assessing blood flow in the brain, transcranial Doppler is making a comeback. Read more »
Rise of the Robots
Radiologists are increasingly finding that robotic systems can offer new dimensions to their practices. Read more » |
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“Every single one of the studies falls into clear methodological errors that invalidate their conclusions. These range from failures to reveal key details about the training and experimental data sets, to not performing robustness or sensitivity analyses of their models, not performing any external validation work, not showing any confidence intervals around the final results (or not revealing the statistical methods used to compute any such), and many more.”
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From Heavenly Bodies to Human Bodies: Astronomer Invents 3D ‘Colposcope’
According to South Carolina’s University of Charleston, personnel from their astronomy department have applied cutting-edge telescope technology into creating the world’s first portable 3D colposcope. The device will assist in early-stage detection of precancer cervical lesions, the researchers say.
Machine Learning Streamlines Process of Sorting Archaeological Fragments
Northern Arizona University scientists announce that a form of machine learning, Convolutional Neural Networks, accurately emulates human thought processes in analyzing visual information. The team successfully applied the technology to efficiently categorizing thousands of pottery fragments, according to the university.
Ingenuity Helicopter Extends Aerial Surveillance of Mars
A bulletin from NASA shares astounding stereo images taken by the Ingenuity Mars Helicopter during a recent survey of our neighboring planet, and explains the algorithm that factors visual clues into the device’s telemetry.
NIR Reveals Modified Image in 15th-Century Religious Text
Using near-infrared imaging, scientists studying an ancient prayer book at the United Kingdom’s Fitzwilliam Museum determined that a rendering of a woman in prayer concealed an earlier image of a different party in prayer, inviting conjecture about European ceremonial customs in the 1400s. |
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